Phentermine

Description

Phentermine pills

Phentermine pills is similar to an amphetamine. It stimulates the central nervous system (nerves and brain), which increases your heart rate and blood pressure and decreases your appetite.

Phentermine is used together with diet and exercise to treat obesity, especially in people with risk factors such as high blood pressure, high cholesterol, or diabetes. Phentermine may also be used for purposes not listed in this medication guide.

Several clinical studies have proven that phentermine can boost fat loss.

The expected average weight loss with phentermine use is 5% of your initial body weight. Yet, over 12 weeks, it can be as high as 10%. This equates to a weight loss of 10–20 pounds (4.5–9 kg) for a 200 pound (90.7 kg) person (8Trusted Source).

In a meta-analysis of six studies, people who took the average dose of 27.5 mg of phentermine for 13 weeks lost an average of 13.9 pounds (6.3 kg) compared to 6.2 pounds (2.8 kg) in placebo groups (9Trusted Source).

While phentermine has been shown to be effective for weight loss, it may work better when combined with topiramate (10Trusted Source).

Topiramate is a drug that has been used on its own to treat seizures but — like phentermine — also has appetite-reducing properties (11Trusted Source, 12Trusted Source, 13Trusted Source).

Topiramate and phentermine is a combination medication sold under the brand name Qsymia.

Compared to three other commonly prescribed drugs for weight loss, the combination of phentermine and topiramate was associated with the highest odds of losing at least 5% of the initial body weight (14Trusted Source).

What’s more, research suggests that the phentermine and topiramate combination is the most effective weight loss medication to date — with people achieving an average weight loss of 21.6 pounds (9.8 kg) after taking the maximum dose for one year (15Trusted Source).

In users, this weight loss has translated to a significant decrease in waist circumference, improved insulin sensitivity, and blood sugar control, as well as favorable effects on triglyceride and cholesterol levels (16Trusted Source, 17Trusted Source).